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Figure IV:

STAGES OF SYMPTOM PROGRESSION IN ALZHEIMER’S DISEASE ©

by Lisa Gwyther, MSW, ACSW

First Stage  2 - 4 years leading up to and including diagnosis:

Symptoms:

  • Recent Memory loss begins to affect job performance

  • Confusion about places - gets lost on way to work.

  • Loses spontaneity, becomes withdrawn, disinterested

  • Mood/personality changes - becomes anxious about symptoms, avoids people.

  • Poor judgment - makes bad decisions.

  • Takes longer with routine chores

  • Trouble handling money, paying bills.

Examples:

  • Forgets which bills are paid and phone numbers that are called frequently.

  • Loses things.  Forgets grocery list.

  • Arrives at wrong time or place, or constantly rechecks calendar or clock.

 

Second Stage  2 - 10 years after diagnosis   (longest stage):

Symptoms:

  • Increasing memory loss and confusion - shorter attention span.

  • Problems recognizing close friends and/or family.

  • Repetitive statements and/or movements.

  • Restless, especially in late afternoon and at night.

  • Occasional muscle twitches or jerking.

  • Perceptual-motor problems

  • Difficulty organizing thoughts, or thinking logically.

  • Can't find right words - makes up stories to fill in the blanks.

  • Problems with reading, writing, and numbers.

  • May be suspicious, irritable, fidgety, teary, or silly.

  • Loss of impulse control - sloppy - won't bathe or afraid to bathe - trouble dressing.

  • Gains and then loses weight.

  • May see or hear things that are not there.

  • Needs full-time supervision.

Examples:

  • Can't remember visits even though the visitor just left.

  • Mixes up day and night, may get up and wander.

  • Difficulty getting into a chair, setting the table for a meal.

  • Can't follow written signs, write name, add or subtract.

  • May accuse spouse of hiding things, infidelity, or childish behavior.

  • May undress at inappropriate times or in wrong place.

  • Forgets when last meal was eaten, may gradually lose interest in food.

Third/terminal stage  1 - 3 years

Symptoms:

  • Can't recognize family or self in mirror.

  • Loses weight even with good diet.

  • Little capacity for self care.  Can't communicate with words.

  • May put anything in mouth or touch anything.

  • Can't control bowels or bladder

  • May have seizures, experience difficulty with swallowing, skin infections.

Examples:

  • Looks in mirror and talks to own image.

  • Needs total care with bathing, dressing, eating and toileting

  • May groan, scream or make grunting noises.

  • Sleeps more, becomes comatose, eventually dies.

 

 

© Gwyther, Lisa P. ACSW, "Care of Alzheimer’s Patients: A Manual for Nursing Home staff." Page 25-27, 1985. Published by The Alzheimer’s Association and the American Health Care Association.  Member, Committee on Patient and Family Services Alzheimer’s Association.  Director, Duke Family Support Program, Center for Aging, Duke University Medical Center

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